Erin Aiello Bowles, MPH
Research interests and experience
- Cancer control: breast cancer; colorectal cancer; biostatistics; epidemiology; mammography; mammographic breast density; cancer treatment; cancer screening and surveillance; automated data collection; quality of care; medication use; natural language processing; care coordination; administrative data
- Women's health: menopause; hormone replacement therapy (HRT); breast cancer
- Health services & economics: access to care; health disparities; health outcomes research; quality of life; measurement of change in health care systems; practice variation
- Aging & geriatrics: cognitive health and dementia; biostatistics; epidemiology; medication use
Epidemiologist Erin Aiello Bowles is looking at cancer and aging from many different perspectives. Her research brings new insight into breast cancer risk factors and treatment, while also helping improve cancer care for patients and families.
As a key member of two large cancer collaborations—the National Cancer Institute (NCI)’s Breast Cancer Surveillance Consortium and the HMO Cancer Research Network (CRN)—Ms. Aiello Bowles has developed diverse expertise that includes reading mammograms for breast density and doing statistical analyses. Her past work with Group Health Research Institute (GHRI) investigators Diana Buist, PhD and Diana Miglioretti, PhD confirmed that breast density is a key breast cancer risk factor. Her work with Ed Wagner, PhD resulted in a key publication showing that certain breast cancer treatments increase the risk of heart failure beyond what had been shown in clinical trials. Ms. Aiello Bowles is also passionate about doing research to help improve the quality of cancer care. She and CRN colleagues were funded through an NCI challenge grant to develop a national breast cancer surgical quality database and evaluate variation in surgical margins across facilities and providers.
Ms. Aiello Bowles’ experience working with large cancer cohorts has provided her with expertise in data collection and management. She has worked with natural language processing programmers to successfully obtain findings from breast pathology and radiology reports. She has worked extensively with administrative data and published several papers on the validity of using health plan data for cancer treatment research. Recently she joined the Adult Changes in Thought study team, and is overseeing their large data repository and data sharing for aging research. She is especially interested in enhancing the efficiency of data collection on these large projects, which has been increasingly important in an era of limited funding.
Boudreau DM, Yu O, Chubak J, Wirtz HS, Bowles EJ, Fujii M, Buist DS. Comparative safety of cardiovascular medication use and breast cancer outcomes among women with early stage breast cancer. Breast Cancer Res Treat. 2014 Apr;144(2):405-16. doi: 10.1007/s10549-014-2870-5. Epub 2014 Feb 21. PubMed
Wirtz HS, Boudreau DM, Gralow JR, Barlow WE, Gray S, Bowles EJ, Buist DS. Factors associated with long-term adherence to annual surveillance mammography among breast cancer survivors. Breast Cancer Res Treat. 2014 Jan 10 [Epub ahead of print]. PubMed
Delate T, Won K, Carroll NM, Kushi L, Hornbrook M, Aiello Bowles EJ, Menter A, Loggers ET, Ritzwoller D. Factors associated with first-line bevacizumab use in advanced, non-squamous, non-small cell lung cancer. J Cancer Res Ther. 2014;2(1):1-8.
Wagner EH, Ludman EJ, Aiello Bowles EJ, Penfold R, Reid RJ, Rutter CM, Chubak J, McCorkle R. Nurse navigators in early cancer care: a randomized, controlled trial. J Clin Oncol. 2013 Nov 25. [Epub ahead of print]. PubMed
Chubak J, Aiello Bowles EJ, Tuzzio L, Ludman E, Rutter CM, Reid RJ, Wagner EH. Perspectives of cancer survivors on the role of different healthcare providers in an integrated delivery system. J Cancer Surviv. 2013 Dec 19 [Epub ahead of print]. PubMed
Onitilo AA, Onesti JK, Single RM, Engel JM, James TA, Aiello Bowles EJ, Feigelson HS, Barney T, McCahill LE. Utilization of neoadjuvant chemotherapy varies in the treatment of women with invasive breast cancer. PLoS One. 2013 Dec 20;8(12):e84535. doi: 10.1371/journal.pone.0084535. PubMed
Onitilo AA, Engel JM, James TA, Aiello Bowles EJ, McCahill LE, Feigelson HS. Reply to: Should initial mastectomy rates increase? J Am Coll Surg. 2013 Nov;217(5):960-2. doi: 10.1016/j.jamcollsurg.2013.07.396. PubMed
Ritzwoller DP, Carroll N, Delate T, O'Keeffe-Rossetti M, Fishman PA, Loggers ET, Aiello Bowles EJ, Elston-Lafata J, Hornbrook MC. Validation of electronic data on chemotherapy and hormone therapy use in HMOs. Med Care. 2013 Oct;51(10):e67-73. doi: 10.1097/MLR.0b013e31824def85. Epub 2012 Apr 23. PubMed
Wirtz HS, Buist DS, Gralow JR, Barlow WE, Gray SL, Chubak J, Yu O, Bowles EJ, Fujii M, Boudreau DM. Frequent antibiotic use and second breast cancer events. Cancer Epidemiol Biomarkers Prev. 2013 Sep;22(9):1588-99. doi:10.1158/1055-9965.EPI-13-0454. Epub 2013 Jul 5. PubMed
Sprague BL, Trentham-Dietz A, Hedman CJ, Wang J, Hemming JD, Hampton JM, Buist DS, Bowles EJ, Sisney GS, Burnside ES. Circulating serum xenoestrogens and mammographic breast density. Breast Cancer Res. 2013 May 27;15(3):R45 [Epub ahead of print]. PubMed
To view more publications, please see Ms. Aiello Bowles’ CV.