Erin Aiello Bowles, MPH
Research interests and experience
- Cancer control: breast cancer; colorectal cancer; biostatistics; epidemiology; mammography; mammographic breast density; cancer treatment; cancer screening and surveillance; automated data collection; quality of care; medication use; natural language processing; care coordination; administrative data
- Women's health: menopause; hormone replacement therapy (HRT); breast cancer
- Health services & economics: access to care; health disparities; health outcomes research; quality of life; measurement of change in health care systems; practice variation
- Aging & geriatrics: cognitive health and dementia; biostatistics; epidemiology; medication use
Epidemiologist Erin Aiello Bowles is looking at cancer and aging from many different perspectives. Her research brings new insight into breast cancer risk factors and treatment, while also helping improve cancer care for patients and families.
As a key member of two large cancer collaborations—the National Cancer Institute (NCI)’s Breast Cancer Surveillance Consortium and the HMO Cancer Research Network (CRN)—Ms. Aiello Bowles has developed diverse expertise that includes reading mammograms for breast density and doing statistical analyses. Her past work with Group Health Research Institute (GHRI) investigators Diana Buist, PhD and Diana Miglioretti, PhD confirmed that breast density is a key breast cancer risk factor. Her work with Ed Wagner, PhD resulted in a key publication showing that certain breast cancer treatments increase the risk of heart failure beyond what had been shown in clinical trials. Ms. Aiello Bowles is also passionate about doing research to help improve the quality of cancer care. She and CRN colleagues were funded through an NCI challenge grant to develop a national breast cancer surgical quality database and evaluate variation in surgical margins across facilities and providers.
Ms. Aiello Bowles’ experience working with large cancer cohorts has provided her with expertise in data collection and management. She has worked with natural language processing programmers to successfully obtain findings from breast pathology and radiology reports. She has worked extensively with administrative data and published several papers on the validity of using health plan data for cancer treatment research. Recently she joined the Adult Changes in Thought study team, and is overseeing their large data repository and data sharing for aging research. She is especially interested in enhancing the efficiency of data collection on these large projects, which has been increasingly important in an era of limited funding.
Wirtz HS, Buist DS, Gralow JR, Barlow WE, Gray SL, Chubak J, Yu O, Bowles EJ, Fujii M, Boudreau DM. Frequent antibiotic use and second breast cancer events. Cancer Epidemiol Biomarkers Prev. 2013 Jul 5 [Epub ahead of print].
Sprague BL, Trentham-Dietz A, Hedman CJ, Wang J, Hemming JD, Hampton JM, Buist DS, Bowles EJ, Sisney GS, Burnside ES. Circulating serum xenoestrogens and mammographic breast density. Breast Cancer Res. 2013 May 27;15(3):R45 [Epub ahead of print]. PubMed
Horner K, Ludman E, McCorkle R, Canfield E, Flaherty L, Min J, Miyoshi J, Lapham B, Bowles EA, Wagner E. An oncology nurse navigator program designed to eliminate gaps in early cancer care. Clin J Oncol Nurs. 2013 Feb 1;17(1):43-8. PubMed
Ritzwoller DP, Carroll N, Delate T, Hornbrook MC, Kushi L, Aiello Bowles EJ, Freml JM, Huang K, Loggers ET. Patterns and predictors of first-line chemotherapy use among adults with advanced non-small cell lung cancer in the Cancer Research Network. Lung Cancer. 2012 Dec;78(3):245-52. doi: 10.1016/j.lungcan.2012.09.008. Epub 2012 Sep 27.
Goddard KA, Aiello Bowles EJ, Spencer Feigelson H, Habel LA, Alford SH, McCarty CA, Nekhlyudov L, Onitilo AA, Rahm AK, Webster JA. Utilization of HER2 genetic treating in a multi-institutional observational study. Am J Manag Care. 2012 Nov;18(11):704-12. PubMed
Aiello Bowles EJ, Boudreau DM, Chubak J, Yu O, Fujii M, Chestnut J, Buist DS. Patient reported discontinuation of endocrine therapy and related side effects among women with early stage breast cancer. J Oncol Prac. Nov 1 2012:e149-57.
Bowles EJ, Wellman R, Feigelson HS, Onitilo AA, Freedman AN, Delate T, Allen LA, Nekhlyudov L, Goddard KA, Davis RL, Habel LA, Yood MU, Magid D, Wagner EH, for the Pharmacovigilance Study Team. Risk of heart failure in breast cancer patients after anthracycline and trastuzumab treatment: a retrospective cohort study. J Natl Cancer Inst. 2012 Sep 5;104(17):1293-305.
Lowry SJ, Sprague BL, Aiello Bowles EJ, Hedman CJ, Hemming J, Hampton JM, Burnside ES, Sisney GA, Buist DS, Trentham-Dietz A. Mammographic breast density and serum phytoestrogen levels. Nutr Cancer. 2012 Aug;64(6):783-9. Epub 2012 Aug 3. PubMed
Romaire MA, Bowles EJ, Anderson ML, Buist DS. Comparative effectiveness of mailed reminder letters on mammography screening compliance. Prev Med. 2012 Aug;55(2):127-30. Epub 2012 May 22. PubMed
Allen LA, Yood MU, Wagner EH, Aiello Bowles EJ, Pardee R, Wellman R, Habel L, Nekhlyudov L, Davis RL, Onitilo AA, Magid DJ; for the Pharmacovigilance Research Group. Performance of claims-based algorithms for identifying heart failure and cardiomyopathy among patients diagnosed with breast cancer. Med Care. 2012 May 25. [Epub ahead of print]. PubMed
To view more publications, please see Ms. Aiello Bowles’ CV.