Katherine M. Newton, PhD
Director of Research & External Affairs
Research interests and experience
- Women’s health: menopause; alternative therapies for menopause; hormone replacement therapy; urinary incontinence; selective estrogen receptor modulators
- Chronic illness management: diabetes care and prevention; management
- Cardiovascular health: cardiovascular health in women; effect of hormone replacement therapy on cardiovascular health
- Alternative approaches to healing: menopause
Katherine Newton is a chronic disease epidemiologist who is passionate about finding ways to help women stay healthy during midlife. Known for her research on menopause, Dr. Newton is a national leader in the search for non-hormonal treatments for menopausal symptoms.
After a 20-year career as a cardiovascular nurse specialist, Dr. Newton pursued her PhD in epidemiology and shifted her focus to epidemiologic research, joining Group Health Research Institute (GHRI) as a postdoctoral fellow in 1995. Dr. Newton focuses on health concerns for women reaching midlife and on menopause in particular. She has two primary research goals. The first is to help women transition through menopause in the healthiest way possible, and she is especially interested in investigating ways to relieve menopause symptoms without using hormone replacement therapy. Her second goal is to ensure that people with diabetes, or at high risk for diabetes, have access to the information and support they need to stay healthy.
Dr. Newton’s 2006 randomized trial of alternative therapies for menopause received widespread interest, leading to several invited talks around the world. Study analyses continue to yield compelling findings, including a 2007 publication linking low libido in menopause to trouble sleeping. She is currently participating in a multisite network of investigators, MsFLASH Finding Lasting Answers for Symptoms and Health. This group has conducted 5 randomized trials testing the efficacy of yoga, exercise, omega-3 fatty acids, escitalopram and low dose estrogen for menopause symptoms. Dr. Newton’s other areas of interest include studying the intersection of women’s health and chronic disease, especially diabetes and cardiovascular disease.
Dr. Newton is a member of several professional organizations, including the North American Menopause Society, the American Diabetes Association, and the American Heart Association. She sits on the latter’s councils on cardiovascular epidemiology and cardiovascular nursing. Dr. Newton has held two faculty appointments at the University of Washington since 1999, as affiliate associate professor in epidemiology and affiliate assistant professor in biobehavioral nursing and health systems.
Newton KM. Isoflavones hold limited promise for the treatment of menopausal vasomotor symptoms. Evid Based Med. 2014 Jun 17. pii: ebmed-2014-110000. doi: 10.1136/ebmed-2014-110000. [Epub ahead of print]. PubMed
Reding K, Zahid M, Cavalieri E, Rogan E, Rarccor B, Atkinson C, Yong M, Newton K, Lampe J. Associations between dietary intake of fruits and vegetables in relation to urinary estrogen DNA adduct ratio. Open J Prev Med. 2014;6(4):429-37. doi: 10.4236/ojpm.2014.46050.
Joffe H, Guthrie KA, LaCroix AZ, Reed SD, Ensrud KE, Manson JE, Newton KM, Freeman EW, Anderson GL, Larson JC, Hunt JR, Shifren J, Rexrode KM, Caan B, Sternfeld B, Carpenter JS, Cohen LS. Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine for vasomotor symptoms: a randomized clinical trial. JAMA Int Med. 2014 May 26. doi: 10.1001/jamainternmed.2014.1891. [Epub ahead of print].
Raebel MA, Ellis JL, Schroeder EB, Xu S, O’Connor PJ, Segal JB, Butler MG, Schmittdiel JA, Kirchner HL, Goodrich GK, Lawrence JM, Nichols GA, Newton KM, Pathak RD, Steiner JF. Intensification of antihyperglycemic therapy among patients with incident diabetes: a Surveillance Prevention and Management of Diabetes Mellitus (SUPREME-DM) study. Pharmacoepidemiol Drug Saf. 2014 Mar 18. doi: 10.1002/pds.3610. [Epub ahead of print].
Newton KM, Reed SD, Nekhyludov L, Grothaus LC, Ludman EJ, Ehrlich K, LaCroix AZ. Factors associated with successful discontinuation of hormone therapy. J Womens Health (Larchmt). 2014 May;23(5):382-8. doi: 10.1089/jwh.2012.4200. Epub 2014 Jan 20. PubMed
Newton KM, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD, Sherman S, Sammel MD, Kroenke K, Larson JC, LaCroix AZ. Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network. Menopause. 2014 Jan;21(1):45-58. doi: 10.1097/GME.0b013e31829337a4. PubMed
Reed SD, Guthrie KA, Newton KM, Anderson GL, Booth-Laforce C, Caan B, Carpenter JS, Cohen LS, Dunn AL, Ensrud KE, Freeman EW, Hunt JR, Joffe H, Larson JC, Learman LA, Rothenberg R, Seguin RA, Sherman KJ, Sternfeld BS, LaCroix AZ. Menopausal quality of life: a RCT of yoga, exercise and omega-3 supplements. Am J Obstet Gynecol. 2014 Mar;210(3):244.e1-11. doi: 10.1016/j.ajog.2013.11.016. Epub 2013 Nov 8. PubMed
Raebel MA, Xu S, Goodrich GK, Schroeder EB, Schmittdiel JA, Segal JB, O'Connor PJ, Nichols GA, Lawrence JM, Kirchner HL, Elston Lafata J, Butler M, Newton KM, Steiner JF. Initial antihyperglycemic drug therapy among 241,327 adults with newly identified diabetes from 2005 through 2010: a surveillance, prevention, and management of diabetes mellitus (SUPREME-DM) study. Ann Pharmacother. 2013;47(10):1280-91. doi: 10.1177/1060028013503624. PubMed
Newton KM, Reed SD, Guthrie KA, Sherman KJ, Booth-LaForce C, Caan B, Sternfeld B, Carpenter JS, Learman LA, Freeman EW, Cohen LS, Joffe H, Anderson GL, Larson JC, Ensrud KE, LaCroix AZ. Efficacy of yoga for vasomotor symptoms: a randomized controlled trial. Menopause. 2014 Apr;21(4):339-46. doi: 10.1097/GME.0b013e31829e4baa. PubMed
Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, Carpenter JS, Anderson GL, Larson JC, LaCroix AZ, Newton KM, Reed SD, Manson JE, Sternfeld B, Freeman EW, Tinker LE, Booth LaForce C. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause. 2014 Apr;21(4):347-54. doi: 10.1097/GME.0b013e31829e40b8. PubMed
To view more publications, please see Dr. Newton’s CV.