Onchee Yu's work as a biostatistician is aimed at issues that have a large public health impact. Her extensive experience in statistical application ranges from breast cancer screening and prevention to pharmaco-epidemiology to vaccine safety and effectiveness.

Ms. Yu has been a key member of Group Health Research Institute's (GHRI) immunization research program for nearly a decade. During her nine years with the Vaccine Safety Datalink, she has contributed to several important projects focused on accurately measuring vaccine effectiveness, including 2003 findings suggesting that the pneumococcal vaccine didn't reduce pneumonia risk in the elderly. Her work also includes studies of childhood immunizations, such as a 2006 study that showed common over-the-counter pain relievers didn't prevent minor skin reactions to the diphtheria-tetanus-pertussis (DTaP) vaccine.

Ms. Yu's more recent research combines her interest in medication use and cancer risk. Collaborating with GHRI investigator Denise Boudreau, PhD, and colleagues, she evaluated the impact of statin use on various cancers, including breast cancer and reproductive organs cancer in women and prostate cancer in men.

Ms. Yu is a member of the American Statistical Association. Her methodological expertise includes case-cohort analysis and survival analysis. Working with GHRI investigator Jennifer Nelson, PhD, she is also beginning to explore residual confounding bias in observational studies, with particular focus on studies of influenza vaccine effectiveness in the elderly.

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Recent publications

Boudreau DM, Yu O, Johnson J. Statin use and cancer risk: a comprehensive review. Expert Opin Drug Saf. 2010 Jul;9(4):603-21. Epub 2010 Apr 9. PubMed

Ross TR, Reid RJ, Fishman P, Yu O, Tufano JT, Larson EB. C-B2-03: patient and clinician experience in a patient-centered medical home demonstration. Clin Med Res. 2010 March;8(1):44.

Reid RJ, Fishman PA, Yu O, Ross TR, Tufano JT, Soman MP, Larson EB. Patient-centered medical home demonstration: a prospective, quasi-experimental, before and after evaluation. Am J Manag Care. 2009;15(9):e71-87. PubMed

Olson JM, Raugi GJ, Nguyen VQ, Yu O, Reiber GE. Guideline concordant venous ulcer care predicts healing in a tertiary care Veterans Affairs Medical Center. Wound Repair Regen. 2009 Sep-Oct;17(5):666-70. PubMed

Jackson LA, Yu O, Nelson J, Belongia EA, Hambidge SJ, Baxter R, Naleway A, Nordin J, Baggs J, Iskander J. Risk of medically attended local reactions following diphtheria toxoid containing vaccines in adolescents and young adults: A Vaccine Safety Datalink study. Vaccine. 2009 Aug 6;27(36):4912-6. Epub 2009 Jun 28. PubMed

Jackson LA, Yu O, Belongia EA, Hambidge SJ, Nelson J, Baxter R, Naleway A, Gay C, Nordin J, Baggs J, Iskander J. Frequency of medically attended adverse events following tetanus and diphtheria toxoid vaccine in adolescents and young adults: a Vaccine Safety Datalink study. BMC Infect Dis. 2009;9:165. PubMed

Yu O, Boudreau DM, Buist DS, Miglioretti DL. Statin use and female reproductive organ cancer risk in a large population-based setting. Cancer Causes Control. 2009 Jul;20(5):609-16. Epub 2008 Nov 30. PubMed

Nelson JC, Jackson M, Yu O, Whitney CG, Bounds L, Bittner R, Zavitkovsky A, Jackson LA. Impact of the introduction of pneumococcal conjugate vaccine on rates of community acquired pneumonia in children and adults. Vaccine. 2008 Sep 8;26(38):4947-54. Epub 2008 Jul 26. PubMed

Boudreau DM, Yu O, Buist DS, Miglioretti DL. Statin use and prostate cancer risk in a large population-based setting. Cancer Causes Control. 2008;19(7):767-74. Epub 2008 Mar 6. PubMed

Jackson LA, Starkovich P, Dunstan M, Yu O, Nelson J, Dunn J, Rees T, Zavitkovsky A, Maus D, Froeschle JE, Decker M. Prospective assessment of the effect of needle length and injection site on the risk of local reactions to the fifth diphtheria-tetanus-acellular pertussis vaccination. Pediatrics. 2008;121(3):e646-52. PubMed

Newton KM, Buist DS, Yu O, Hartsfield CL, Andrade SE, Wei F, Connelly MT, Chan KA. Hormone therapy initiation after the Women's Health Initiative. Menopause. 2008;15(3):487-93. Epub 2008 Jan 9. PubMed

Jackson LA, Neuzil KM, Nahm MH, Whitney CG, Yu O, Nelson JC, Starkovich PT, Dunstan M, Carste B, Shay DK, Baggs J, Carlone GM. Immunogenicity of varying dosages of 7-valent pneumococcal polysaccharide-protein conjugate vaccine in seniors previously vaccinated with 23-valent pneumococcal polysaccharide vaccine. Vaccine. 2007;25(20):4029-37. Epub 2007 Mar 12. PubMed

To view more publications, please see Ms. Yu's CV.

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