Radiology Evaluation and Breast Density (READ)

Principal Investigator: Diana Buist
Co-Investigators: Katherine Newton, Erin Bowles, Susan Reed
Funder:  Department of Defense
Project Dates:   June 1, 2003 – June 30, 2008

Abstract:
Short-term HRT cessation prior to receipt of a screening mammogram has the possibility of reducing breast density and improving mammography performance.  Our hypothesis is that cessation of HRT one or two months prior to a screening mammogram improve its performance by decreasing breast density.

Primary aims are to test:

  1. Whether hormone therapy cessation 1 or 2 months before a screening mammogram reduces the likelihood of receiving a recommendation for additional evaluation compared to women who continue using hormone therapy.
  2. Whether duration of hormone therapy cessation affects the likelihood of receiving a recommendation for additional evaluation.
  3. Whether breast density changes among women by trial arm.

Publications: None to date.

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