Jennifer McClure, PhD

“We create programs and tools to empower people and help them lead healthier lives. By doing so, we can reduce the need for health care and the growing burden of health care costs for all.”

Jennifer McClure, PhD

Group Health Research Institute Senior Investigator
Director of Research, Faculty & Development


For nearly 20 years Jennifer McClure has sought to help  people lead healthier lives. Her goal is to develop new interventions which reduce  people’s risk of chronic disease and cancer or help them better manage existing  disease. Her work includes interventions to promote smoking cessation, dietary improvement,  increased physical activity, treatment adherence, better oral health, and  informed decision making.

A unique feature of much of Dr. McClure’s work is the  emphasis on creating highly-individualized treatment programs that can be  disseminated on a population level, through health care systems, tobacco  quitlines, the internet, or smart phones. Her goal is to design programs which  are effective, convenient to use, attractive to real people, and cost-effective  to deliver. She understands that interventions which do not meet these criteria  will have a harder time making the leap from research to real world.

Dr. McClure is best known for her research creating new treatments for  nicotine dependence. This work demonstrated the effectiveness of proactively counseling women by phone to motivate and support smoking cessation, the  effectiveness of Web-based treatment programs, and the potential risks of screening  smokers’ lung functioning to motivate quitting when individuals do not have  demonstrable lung impairment.

Dr. McClure’s current research is identifying key content and  design features which improve the effectiveness of online smoking cessation  programs, evaluating the effectiveness of Acceptance and Commitment Therapy for  smoking cessation, and designing eHealth and mHealth tools to help smokers  better manage nicotine withdrawal symptoms and medication side-effects which  can contribute to relapse and treatment failure.

Dr. McClure frequently collaborates with colleagues at the Fred Hutchinson Cancer Research Center; the University of California, Davis; the University of Michigan Center for Health Communications Research; and Alere Wellbeing.

In recognition of her contributions to the field of  behavioral medicine, Dr. McClure was named a fellow in the Society of Behavioral Medicine in 2013. She is also  Associate Editor of Nicotine & Tobacco Research and co-chair of the Society for  Research on Nicotine and Tobacco’s Treatment Network.

Dr. McClure is an Affiliate Professor in the  Department of Health Services in the University of Washington's School of Public Health and an Affiliate Investigator in the Division of Public Health  Sciences at the Fred Hutchinson Cancer Research Center. In 2008 she was named Associate Director of  Research, Internal at GHRI, and in  2013 named Director of Research, Faculty & Development.


  • Behavior Change & Health Promotion

    Tobacco cessation; pharmocogenomics of nicotine addiction; treatment adherence; population-based behavior interventions; health risk communications and informed decision-making

  • Health Informatics

    Development of eHealth and mHealth intervention tools

  • Mental Health

  • Cancer


Recent publications

Kendall L, Eschler J, Lozano P, McClure JB, Vizer LM, Ralston JD, Pratt W.

Engineering for reliability in at-home chronic disease management.

AMIA Annu Symp Proc. 2014. 777-86.

Bergen AW, Javitz HS, Krasnow R, Michel M, Nishita D, Conti DV, Edlund CK, Kwok PY, McClure JB, Kim RB, Hall S, Tyndale RF, Baker TB, Benowitz NL, Swan GE.

Organic cation transporter variation and response to smoking cessation therapies.

Nicotine Tob Res. 2014 Aug 20. pii: ntu161 [Epub ahead of print]. PubMed

Cano MA, Lam CY, Chen M, Adams CE, Correa-Fernandez V, Stewart DW, McClure JB, Cinciripini PM, Wetter DW.

Positive smoking outcome expectancies mediate the association between negative affect and smoking urge among women during a quit attempt.

Exp Clin Psychopharmacol. 2014 May 5 [Epub ahead of print]. PubMed

McClure JB, Peterson D, Derry H, Riggs K, Saint-Johnson J, Nair V, An L, Shortreed SM.

Exploring the "active ingredients" of an online smoking intervention: a randomized factorial trial.

Nicotine Tob Res. 2014 Aug;16(8):1129-39. doi: 10.1093/ntr/ntu057. Epub 2014 Apr 11. PubMed